Article
Expression efficiency of NAT2 haplotypes in a Korean population.
Genes & genetic systems - 4 Apr 2017
Na Han Sung, Lee Jin Sol, Cheong Hyun Sub, Shin Hee Jung, Kang Tae Sun, Park Hyun Joo, Shin Hyoung Doo, Chung Myeon Woo
Abstract excerpt
Since NAT2 single-nucleotide polymorphisms (SNPs) are responsible for the efficacy of arylamines and hydrazine drugs, defining the effects of these SNPs in various ethnicities is an important factor in the development of personalized medicine. In the present study, we examined the expression efficiency of NAT2 using promoter haplotypes identified in a Korean population. To construct NAT2 promoter haplotypes,...
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