Article
Arylamine N-acetyltransferase 2 genotypes in a Mexican population.
Genetics and molecular research : GMR - 27 Apr 2012
Taja-Chayeb L, Agúndez J A, Miguez-Muñoz C, Chavez-Blanco A, Dueñas-Gonzalez A
Abstract excerpt
The acetylating activity of N-acetyltransferase 2 (NAT2) has critical implications for therapeutics and disease susceptibility. To date, several polymorphisms that alter the enzymatic activity and/or protein stability of NAT2 have been identified. We examined the distribution and frequency of NAT2 genotypes in the Mexican population. Among 250 samples amplified and sequenced for the NAT2 gene, we found seven...
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