Article
Association between NAT2 polymorphisms and the risk of schizophrenia in a Northern Chinese Han population.
Psychiatric genetics - 1 Apr 2017
Luan Zhilin, Lu Tianlan, Yue Weihua, Copray Sjef, Zhang Dai
Abstract excerpt
The gene that encodes N-acetyltransferase 2 (NAT2), an enzyme that plays a crucial role in the metabolism of many drugs and xenobiotics, is located on chromosome 8p22, one of the most convictive susceptibility loci of schizophrenia. NAT2 genetic polymorphisms lead to various enzyme acetylation phenotypes. In the present study, six selected NAT2 exonic single nucleotide polymorphisms were genotyped in an...
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