Article
Functional characterization of single-nucleotide polymorphisms and haplotypes of human N-acetyltransferase 2.
Carcinogenesis - 1 Aug 2007
Zang Yu, Doll Mark A, Zhao Shuang, States J Christopher, Hein David W
Abstract excerpt
Human N-acetyltransferase 2 (NAT2) is polymorphic in humans and may associate with cancer risk by modifying individual susceptibility to cancers from carcinogen exposure. Since molecular epidemiological studies investigating these associations usually include determining NAT2 single-nucleotide polymorphisms (SNPs), haplotypes or genotypes, their conclusions can be compromised by the uncertainty of...
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