Article
Sequence analysis of the N-acetyltransferase 2 gene (NAT2) among Jordanian volunteers.
The Libyan journal of medicine - 1 Dec 2018
Jarrar Yazun Bashir, Balasmeh Ayat Ahmed, Jarrar Wassan
Abstract excerpt
The present study aimed to identify the NAT2 haplotypes, linkage disequilibrium, and novel NAT2 genetic variants among Jordanian population. We isolated the genomic DNA from 68 healthy, Arab, unrelated Jordanian volunteers to amplify the protein-coding region of NAT2 gene by polymerase chain reaction (PCR). Then, the amplified PCR products were sequenced using Applied Biosystems Model (ABI3730x1). It is found...
Topics
- Adult
- Arabs
- Arylamine N-Acetyltransferase
- Female
- Gene Frequency
- Genetic Variation
- Haplotypes
- Healthy Volunteers
- Humans
- Jordan
- Male
- Sequence Analysis, DNA
