Article
Association of CTG repeat polymorphism in carnosine dipeptidase 1 (CNDP1) gene with diabetic nephropathy in north Indians.
The Indian journal of medical research - 1 Jul 2016
Yadav Ashok K, Sinha Nisha, Kumar Vinod, Bhansali Anil, Dutta Pinaki, Jha Vivekanand
Abstract excerpt
BACKGROUND & OBJECTIVES: CNDP1 gene, present on chromosome 18q22.3-23, encodes carnosinase, the rate-limiting enzyme in hydrolysis of carnosine to ß-alanine and L-histidine. Linkage of CTG trinucleotide (leucine) repeat polymorphism in CNDP1 gene with diabetic nephropathy has been observed in several populations. However, this association is conflicting and population-dependent. We investigated this association...
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