Article
CNDP1 and Diabetic Kidney Disease: From Genetic Susceptibility to Therapeutic Targeting.
Genes - 24 Mar 2026
Delibasi Bulent Tolga, Sarisen Michael Ismail, Belitsos Matthew Thomas, Erol Halil Kutlu, Delibasi Tuncay
Abstract excerpt
Diabetic kidney disease (DKD) affects a substantial proportion of individuals with diabetes mellitus and represents the leading cause of end-stage renal disease worldwide. Familial aggregation studies consistently demonstrate that genetic factors contribute significantly to DKD susceptibility beyond metabolic and hemodynamic determinants. The carnosine dipeptidase 1 (CNDP1) gene on chromosome 18q22.3 has emerged...
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