Article
Association of variants in the carnosine peptidase 1 gene (CNDP1) with diabetic nephropathy in American Indians.
Molecular genetics and metabolism - 1 Jun 2011
Chakkera Harini A, Hanson Robert L, Kobes Sayuko, Millis Meredith P, Nelson Robert G, Knowler William C, Distefano Johanna K
Abstract excerpt
CNDP1 is located on 18q22.3, where linkage with diabetic nephropathy has been observed in several populations, including Pima Indians. However, evidence for association between CNDP1 alleles and diabetic nephropathy is equivocal and population-dependent. This study investigated CNDP1 as a candidate for diabetic kidney disease in Pima Indians. Nineteen tag single nucleotide polymorphisms spanning the CNDP1 locus...
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