Article
The influence of a single nucleotide polymorphism within CNDP1 on susceptibility to diabetic nephropathy in Japanese women with type 2 diabetes.
PloS one - 1 Jan 2013
Kurashige Mahiro, Imamura Minako, Araki Shin-Ichi, Suzuki Daisuke, Babazono Tetsuya, Uzu Takashi, Umezono Tomoya, Toyoda Masao, Kawai Koichi, Imanishi Masahito, Hanaoka Kazushige, Maegawa Hiroshi, Uchigata Yasuko, Hosoya Tatsuo, Maeda Shiro
Abstract excerpt
BACKGROUND: Several linkage analyses have mapped a susceptibility locus for diabetic nephropathy to chromosome 18q22-23, and polymorphisms within the carnosine dipeptidase 1 gene (CNDP1), located on 18q22.3, have been shown to be associated with diabetic nephropathy in European subjects with type 2 diabetes. However, the association of this locus with diabetic nephropathy has not been evaluated in the Japanese...
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