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Article

A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Apr 2007

Freedman Barry I, Hicks Pamela J, Sale Michele M, Pierson Eric D, Langefeld Carl D, Rich Stephen S, Xu Jianzhao, McDonough Caitrin, Janssen Bart, Yard Benito A, van der Woude Fokko J, Bowden Donald W

Abstract excerpt

BACKGROUND: Four linkage analyses have identified a region on chromosome 18q22-23 that appears to harbour a diabetic nephropathy (DN) susceptibility locus. A trinucleotide repeat sequence in exon 2 of the carnosinase gene (CNDP1) residing on 18q22.3 was subsequently associated with DN in European Caucasians and Arabs. METHODS: We evaluated the role of the CNDP1 5 leucine/5 leucine (5-5) polymorphism (CNDP1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17205963
DOI: 10.1093/ndt/gfl717

Genes

CNDP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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