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Article

A CTG polymorphism in the CNDP1 gene determines the secretion of serum carnosinase in Cos-7 transfected cells.

Diabetes - 1 Sept 2007

Riedl Eva, Koeppel Hannes, Brinkkoetter Paul, Sternik Paula, Steinbeisser Herbert, Sauerhoefer Sibylle, Janssen Bart, van der Woude Fokko J, Yard Benito A

Abstract excerpt

Recently, we demonstrated that a polymorphism in exon 2 of the serum carnosinase (CNDP1) gene is associated with susceptibility to developing diabetic nephropathy. Based on the number of CTG repeats in the signal peptide, five different alleles coding for 4, 5, 6, 7, or 8 leucines (4L-8L) are known. Diabetic patients without nephropathy are homozygous for the 5L allele more frequently than those with nephropathy....

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Source

Identifiers

PMID: 17601991
DOI: 10.2337/db07-0128

Genes

CNDP1
ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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