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Article

Common variants in CNDP1 and CNDP2, and risk of nephropathy in type 2 diabetes.

Diabetologia - 1 Sept 2011

Ahluwalia T S, Lindholm E, Groop L C

Abstract excerpt

AIMS/HYPOTHESIS: Several genome-wide linkage studies have shown an association between diabetic nephropathy and a locus on chromosome 18q harbouring two carnosinase genes, CNDP1 and CNDP2. Carnosinase degrades carnosine (β-alanyl-L-histidine), which has been ascribed a renal protective effect as a scavenger of reactive oxygen species. We investigated the putative associations of genetic variants in CNDP1 and...

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Identifiers

PMID: 21573905
DOI: 10.1007/s00125-011-2178-5

Genes

CNDP1
CNDP2

Provenance

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Related research

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Common variants in CNDP1 and CNDP2, and risk of nephropathy in type 2 diabetes.PMID 21573905Read ↗

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The influence of carnosinase gene polymorphisms on diabetic nephropathy risk in African-Americans.Semantic proximity Read ↗

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