Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

α-Catenin stabilises Cadherin-Catenin complexes and modulates actomyosin dynamics to allow pulsatile apical contraction.

Journal of cell science - 15 Dec 2016

Jurado Jaime, de Navascués Joaquín, Gorfinkiel Nicole

Abstract excerpt

We have investigated how cell contractility and adhesion are functionally integrated during epithelial morphogenesis. To this end, we have analysed the role of α-Catenin, a key molecule linking E-Cadherin-based adhesion and the actomyosin cytoskeleton, during Drosophila embryonic dorsal closure, by studying a newly developed allelic series. We find that α-Catenin regulates pulsatile apical contraction in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin Cytoskeleton
Share to Actomyosin
Share to alpha Catenin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cadherins

Share to Cell Adhesion Molecules

Share to Cell Polarity

Share to Intercellular Junctions

Share to Vinculin

Source

Identifiers

PMID: 27831494
DOI: 10.1242/jcs.193268

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

α-Catenin stabilises Cadherin-Catenin complexes and modulates actomyosin dynamics to allow pulsatile apical contraction.PMID 27831494Read ↗

Cadherin mechanotransduction in tissue remodeling.Semantic proximity Read ↗

Monomeric α-catenin links cadherin to the actin cytoskeleton.Semantic proximity Read ↗

Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin networkSemantic proximity Read ↗

Dynamic features of adherens junctions during Drosophila embryonic epithelial morphogenesis revealed by a Dalpha-catenin-GFP fusion protein.Semantic proximity Read ↗

p120-catenin controls contractility along the vertical axis of epithelial lateral membranes.Semantic proximity Read ↗

A contractile actomyosin network linked to adherens junctions by Canoe/afadin helps drive convergent extension.Semantic proximity Read ↗

Mutational analysis supports a core role for Drosophila α-catenin in adherens junction function.Semantic proximity Read ↗

Sisyphus, the Drosophila myosin XV homolog, traffics within filopodia transporting key sensory and adhesion cargos.Semantic proximity Read ↗

p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis.Semantic proximity Read ↗

Multivalent interactions make adherens junction-cytoskeletal linkage robust during morphogenesis.Semantic proximity Read ↗

DRhoGEF2 regulates cellular tension and cell pulsations in the Amnioserosa during Drosophila dorsal closure.Semantic proximity Read ↗

Convergent extension requires adhesion-dependent biomechanical integration of cell crawling and junction contractionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.