Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sisyphus, the Drosophila myosin XV homolog, traffics within filopodia transporting key sensory and adhesion cargos.

Development (Cambridge, England) - 1 Jan 2008

Liu Raymond, Woolner Sarah, Johndrow James E, Metzger David, Flores Adriana, Parkhurst Susan M

Abstract excerpt

Unconventional myosin proteins of the MyTH-FERM superclass are involved in intrafilopodial trafficking, are thought to be mediators of membrane-cytoskeleton interactions, and are linked to several forms of deafness in mammals. Here we show that the Drosophila myosin XV homolog, Sisyphus, is expressed at high levels in leading edge cells and their cellular protrusions during the morphogenetic process of dorsal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cadherins
Share to Cell Adhesion

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Embryo, Nonmammalian

Share to Myosins

Share to Neurons, Afferent

Share to Protein Transport

Share to Pseudopodia

Source

Identifiers

PMID: 18045836
DOI: 10.1242/dev.011437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sisyphus, the Drosophila myosin XV homolog, traffics within filopodia transporting key sensory and adhesion cargos.PMID 18045836Read ↗

<i>Drosophila</i> Short stop as a paradigm for the role and regulation of spectraplakinsSemantic proximity Read ↗

Myosin 7 and its adaptors link cadherins to actin.Semantic proximity Read ↗

Analysis of the cell adhesion molecule sticks-and-stones reveals multiple redundant functional domains, protein-interaction motifs and phosphorylated tyrosines that direct myoblast fusion in Drosophila melanogaster.Semantic proximity Read ↗

The spectraplakin Short stop is an essential microtubule regulator involved in epithelial closure in Drosophila.Semantic proximity Read ↗

Myosins: Tails (and Heads) of Functional DiversitySemantic proximity Read ↗

Caenorhabditis elegans SORB-1 localizes to integrin adhesion sites and is required for organization of sarcomeres and mitochondria in myocytes.Semantic proximity Read ↗

α-Catenin stabilises Cadherin-Catenin complexes and modulates actomyosin dynamics to allow pulsatile apical contraction.Semantic proximity Read ↗

The Drosophila F-box protein Fbxl7 binds to the protocadherin fat and regulates Dachs localization and Hippo signaling.Semantic proximity Read ↗

Polarized Rac-dependent protrusions drive epithelial intercalation in the embryonic epidermis of C. elegansSemantic proximity Read ↗

Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complex.Semantic proximity Read ↗

Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression in Drosophila.Semantic proximity Read ↗

Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.