Article
p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis.
Development (Cambridge, England) - 1 Aug 2014
Lang Richard A, Herman Ken, Reynolds Albert B, Hildebrand Jeffrey D, Plageman Timothy F
Abstract excerpt
Apical constriction (AC) is a widely utilized mechanism of cell shape change whereby epithelial cells transform from a cylindrical to conical shape, which can facilitate morphogenetic movements during embryonic development. Invertebrate epithelial cells undergoing AC depend on the contraction of apical cortex-spanning actomyosin filaments that generate force on the apical junctions and pull them toward the middle...
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