Article
Cadherin mechanotransduction in tissue remodeling.
Cellular and molecular life sciences : CMLS - 1 Nov 2013
Twiss Floor, de Rooij Johan
Abstract excerpt
Mechanical forces are increasingly recognized as central factors in the regulation of tissue morphogenesis and homeostasis. Central to the transduction of mechanical information into biochemical signaling is the contractile actomyosin cytoskeleton. Fluctuations in actomyosin contraction are sensed by tension sensitive systems at the interface between actomyosin and cell adhesion complexes. We review the current...
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