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Article

A contractile actomyosin network linked to adherens junctions by Canoe/afadin helps drive convergent extension.

Molecular biology of the cell - 15 Jul 2011

Sawyer Jessica K, Choi Wangsun, Jung Kuo-Chen, He Li, Harris Nathan J, Peifer Mark

Abstract excerpt

Integrating individual cell movements to create tissue-level shape change is essential to building an animal. We explored mechanisms of adherens junction (AJ):cytoskeleton linkage and roles of the linkage regulator Canoe/afadin during Drosophila germband extension (GBE), a convergent-extension process elongating the body axis. We found surprising parallels between GBE and a quite different morphogenetic movement,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21613546
DOI: 10.1091/mbc.E11-05-0411
PMCID: PMC3135475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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