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Article

Donor and recipient genetic variants in NLRP3 associate with early acute rejection following kidney transplantation.

Scientific reports - 7 Nov 2016

Dessing Mark C, Kers Jesper, Damman Jeffrey, Navis Gerjan J, Florquin Sandrine, Leemans Jaklien C

Abstract excerpt

NLRP3 (NOD-like receptor family, pyrin domain containing 3) is a member of the inflammasome family and is of special interest in renal disease. Experimental studies have shown that Nlrp3 plays a significant role in the induction of renal damage and dysfunction in acute and chronic renal injury. However, the role of NLRP3 in human renal disease is completely unknown. From a retrospective cohort study, we...

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Source

Open in PubMed Open full text

Identifiers

PMID: 27819323
DOI: 10.1038/srep36315
PMCID: PMC5098240

Genes

NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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