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Article

Common variants in NLRP2 and NLRP3 genes are strong prognostic factors for the outcome of HLA-identical sibling allogeneic stem cell transplantation.

Blood - 15 Nov 2008

Granell Miquel, Urbano-Ispizua Alvaro, Pons Aina, Aróstegui Juan Ignacio, Gel Bernat, Navarro Alfons, Jansa Sonia, Artells Rosa, Gaya Anna, Talarn Carme, Fernández-Avilés Francesc, Martínez Carmen, Rovira Montserrat, Carreras Enric, Rozman Ciril, Juan Manel, Yagüe Jordi, Montserrat Emili, Monzó Mariano

Abstract excerpt

The inflammasomes are macromolecular cytosolic complexes involved in the production of interleukin-1beta (IL-1beta) and IL-18 in response to several pathogen-derived stimuli. Such interleukins have been implicated in the origin of severe allogeneic stem cell transplant (allo-SCT) complications. W...

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Source

Identifiers

PMID: 18772453
DOI: 10.1182/blood-2007-12-129247

Genes

SCT
NLRP2
NLRP3
NLRP1
CARD8
CASP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18772453-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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