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Article

The association between single nucleotide polymorphisms in NLRP gene and diabetic nephropathy.

Nefrologia - 1 Oct 2025

Badr Eman A E, Toulan Safwa O, El Ghobashy Yasser A, Nofal Ahmed Mostafa, Assar Mohamed F A

Abstract excerpt

BACKGROUND: Diabetic nephropathy (DN) is a major cause of chronic kidney disease, influenced by genetic and inflammatory factors. SNPs in NLRP1 and NLRP3 genes, key regulators of inflammation, may contribute to DN susceptibility, offering insights into its pathogenesis and potential therapeutic targets. This study aims to investigate the association between single nucleotide polymorphisms (SNPs) in NLRP1 and...

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Source

Identifiers

PMID: 41173589
DOI: 10.1016/j.nefroe.2025.501339

Genes

NLRP1
NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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