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Article

LIM Zinc Finger Domain Containing 1 Risk Genotype of Recipient Is Associated with Renal Tubular Inflammation in Kidney Transplantation.

Genes - 13 Jun 2024

Caliskan Yasar, Ozluk Yasemin, Kurashima Kento, Mirioglu Safak, Dirim Ahmet Burak, Hurdogan Ozge, Oto Ozgur Akin, Syn Marzena, Nazzal Mustafa, Jain Ajay, Edwards John, Yazici Halil, Lentine Krista L

Abstract excerpt

BACKGROUND: Homozygosity for LIMS1 rs893403-GG genotype is linked to an increased risk of allograft rejection after kidney transplantation. Ischemia-reperfusion of the kidney allograft leads to long term infiltration of activated and effector-memory T lymphocytes and resulting in rejection and long-term fibrosis. However, the genotype, LIMS1 expression under ischemic conditions and the long-term histopathological...

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Identifiers

PMID: 38927709
DOI: 10.3390/genes15060773
PMCID: PMC11203101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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