Article
The functional polymorphism Ala258Ser in the innate receptor gene ficolin-2 in the donor predicts improved renal transplant outcome.
Transplantation - 15 Sept 2012
Eikmans Michael, de Canck Ilse, van der Pol Pieter, Baan Carla C, Haasnoot Geert W, Mallat Marko J K, Vergunst Manon, de Meester Els, Roodnat Joke I, Anholts Jacqueline D H, van Thielen Martine, Doxiadis Ilias I N, de Fijter Johan W, van der Linden Pieter J E, van Beelen Els, van Kooten Cees, Kal-van Gestel Judith A, Peeters Annemiek M A, Weimar Willem, Roelen Dave L, Rossau Rudi, Claas Frans H J
Abstract excerpt
BACKGROUND: Innate immunity plays a role in controlling adaptive immune responses. METHODS: We investigated the clinical relevance of single nucleotide polymorphisms in 22 genes encoding innate, secreted, and signaling pattern recognition receptors in a total of 520 donor-recipient pairs of postm...
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