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Article

Liver Monocytes and Kupffer Cells Remain Transcriptionally Distinct during Chronic Viral Infection.

PloS one - 1 Jan 2016

van de Garde Martijn D B, Movita Dowty, van der Heide Marieke, Herschke Florence, De Jonghe Sandra, Gama Lucio, Boonstra Andre, Vanwolleghem Thomas

Abstract excerpt

Due to the scarcity of immunocompetent animal models for chronic viral hepatitis, little is known about the role of the innate intrahepatic immune system during viral replication in the liver. These insights are however fundamental for the understanding of the inappropriate adaptive immune responses during the chronic phase of the infection. We apply the Lymphocytic Choriomenigitis Virus (LCMV) clone 13 mouse...

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Share to Antigens, Viral
Share to Hepatitis B, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mice, Inbred C57BL

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Share to Transcription, Genetic

Source

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Identifiers

PMID: 27812182
DOI: 10.1371/journal.pone.0166094
PMCID: PMC5094584

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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