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Article

Phenotype and fate of liver-resident CD8 T cells during acute and chronic hepacivirus infection.

PLoS pathogens - 1 Oct 2023

Dravid Piyush, Murthy Satyapramod, Attia Zayed, Cassady Cole, Chandra Rahul, Trivedi Sheetal, Vyas Ashish, Gridley John, Holland Brantley, Kumari Anuradha, Grakoui Arash, Cullen John M, Walker Christopher M, Sharma Himanshu, Kapoor Amit

Abstract excerpt

Immune correlates of hepatitis C virus (HCV) clearance and control remain poorly defined due to the lack of an informative animal model. We recently described acute and chronic rodent HCV-like virus (RHV) infections in lab mice. Here, we developed MHC class I and class II tetramers to characterize the serial changes in RHV-specific CD8 and CD4 T cells during acute and chronic infection in C57BL/6J mice. RHV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37812637
DOI: 10.1371/journal.ppat.1011697
PMCID: PMC10602381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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