Article
Innate Immunity in Hepatitis C Virus Infection.
Cold Spring Harbor perspectives in medicine - 1 Feb 2021
Schwerk Johannes, Negash Amina, Savan Ram, Gale Michael
Abstract excerpt
Activation and viral control of the innate immune response are hallmarks of hepatitis C virus (HCV) infection and are major determinants of spontaneous clearance or progression to chronic infection and liver disease. In this review, we provide a contemporary overview of how HCV is sensed by the host cell to trigger innate immune activation and the mechanisms deployed by the virus to evade this response. Type I...
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