Efficient Screening of CRISPR/Cas9-Induced Events in Drosophila Using a Co-CRISPR Strategy.

Abstract excerpt

Genome editing using the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and associated nuclease (Cas9) enables specific genetic modifications, including deletions, insertions, and substitutions in numerous organisms, such as the fruit fly Drosophila melanogaster One challenge...

Topics

• Animals
• Animals, Genetically Modified
• CRISPR-Cas Systems
• DNA-Binding Proteins
• Drosophila Proteins
• Drosophila melanogaster
• Gene Editing
• Gene Targeting
• INDEL Mutation
• Phenotype