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Article

Construction and Analysis of an Allelic Series of Ccn1 Knockin Mice.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Monzon Ricardo I, Kim Ki-Hyun, Lau Lester F

Abstract excerpt

The embryonic lethality of mice with conventional global knockout of Ccn1 (Cyr61) precludes analysis of Ccn1 functions in late embryonic development or in adulthood. To circumvent this limitation, we have generated conditional knockout mice that allow cell type-specific deletion of Ccn1, and constructed an allelic series of Ccn1 knockin mice that express CCN1 defective for binding specific integrins in lieu of...

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Identifiers

PMID: 27734389
DOI: 10.1007/978-1-4939-6430-7_30

Genes

CCN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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