Article
A method for the generation of conditional gene-targeted mice.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Yamamoto Masahiro, Takeda Kiyoshi
Abstract excerpt
Integrins and cell adhesion molecules are required for cell adhesion and movement, as well as various biological functions such as development or immune responses. To elucidate their in vivo functions, mice lacking these molecules have been generated and various phenotypes analyzed. In the case of embryonic lethality or a requirement for spatiotemporal ablation of these genes, conditional gene-targeted mice have...
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