Article

Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission

2022-05-13

Abstract excerpt

Schizophrenia affects approximately 1% of the world population. Genetics, epigenetics, and environmental factors are known to play a role in this psychiatric disorder. While there is a high concordance in monozygotic twins, about half of twin pairs are discordant for schizophrenia. We characterized human-induced pluripotent stem cell (iPSC)-derived hippocampal neurons from two pairs of monozygotic twins that are d...

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Literature Corpus work: 730b1235-51fe-5b37-a4e2-b447df54b0a9
DOI: 10.1101/2022.05.13.491776

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