Article
Contribution of induced pluripotent stem cell technologies to the understanding of cellular phenotypes in schizophrenia.
Neurobiology of disease - 1 Nov 2019
Balan Shabeesh, Toyoshima Manabu, Yoshikawa Takeo
Abstract excerpt
Schizophrenia is one of the leading causes of disability among mental disorders, contributing to a substantial socioeconomic burden. Our understanding of the mechanisms of the pathogenesis of the disease has largely been limited by its inherent complexity imparted by the polygenicity and interactions with environmental factors. Since pathobiological events are initiated in the schizophrenic brain long before the...
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