Article
In vivo analysis of internal ribosome entry at the Hairless locus by genome engineering in Drosophila.
Scientific reports - 7 Oct 2016
Smylla Thomas K, Preiss Anette, Maier Dieter
Abstract excerpt
Cell communication in metazoans requires the highly conserved Notch signaling pathway, which is subjected to strict regulation of both activation and silencing. In Drosophila melanogaster, silencing involves the assembly of a repressor complex by Hairless (H) on Notch target gene promoters. We previously found an in-frame internal ribosome entry site in the full length H transcript resulting in two H protein...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
