Article

Functional mapping of the mouse <i>hairless</i> gene promoter region

2018-01-08

Abstract excerpt

The mouse hairless gene ( Hr ) encodes a protein of 127 kDa, acting as corepressor of nuclear hormone receptors. The Hairless protein (HR) is involved in the control of the cellular transition to the first hair cycle in adult Mammals. In its absence hair follicles disintegrate leading to a complete and irreversible hair loss with formation of cutaneous cysts. The hairless phenotype is therefore linked to defecti...

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Literature Corpus work: cc880b80-4fd6-51a9-8d98-f2ba7ec6e37f
DOI: 10.1101/244426

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