Homeless is required for RNA localization in Drosophila oogenesis and encodes a new member of the DE-H family of RNA-dependent ATPases.

doi:10.1101/gad.9.20.2495

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Article

Homeless is required for RNA localization in Drosophila oogenesis and encodes a new member of the DE-H family of RNA-dependent ATPases.

Genes & development - 15 Oct 1995

Gillespie D E, Berg C A

Abstract excerpt

The homeless (hls) gene of Drosophila is required for anteroposterior and dorsoventral axis formation during oogenesis. At a low frequency, females homozygous for mutations in hls generate early egg chambers in which the oocyte is positioned incorrectly within the cyst. At a high frequency, late-stage egg chambers exhibit a ventralized chorion. Sequence analysis of the hls cDNA predicts a protein with...

Topics

Adenosine Triphosphatases
Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
DNA, Complementary
Drosophila
Drosophila Proteins
Egg Shell
Female
Homozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microtubules

Molecular Sequence Data

Oocytes

Oogenesis

Phenotype

RNA

Sequence Homology, Amino Acid

Source

Open in PubMed

Identifiers

PMID: 7590230
DOI: 10.1101/gad.9.20.2495

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7590230-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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