Article
The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport.
The EMBO journal - 15 May 2003
Bullock Simon L, Zicha Daniel, Ish-Horowicz David
Abstract excerpt
In several Drosophila cell types, mRNA transport depends on microtubules, the molecular motor dynein and trans-acting factors including Egalitarian and Bicaudal-D. However, the molecular basis of transcript recognition by the localization machinery is poorly understood. Here, we characterize the features of hairy pair-rule RNA transcripts that mediate their apical localization, using in vivo injection of...
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