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Article

Membrane-Anchored Hairless Protein Restrains Notch Signaling Activity.

Genes - 6 Nov 2020

Maier Dieter

Abstract excerpt

The Notch signaling pathway governs cell-to-cell communication in higher eukaryotes. In Drosophila, after cleavage of the transmembrane receptor Notch, the intracellular domain of Notch (ICN) binds to the transducer Suppressor of Hairless (Su(H)) and shuttles into the nucleus to activate Notch target genes. Similarly, the Notch antagonist Hairless transfers Su(H) into the nucleus to repress Notch target genes....

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Identifiers

PMID: 33171957
DOI: 10.3390/genes11111315
PMCID: PMC7694644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Membrane-Anchored Hairless Protein Restrains Notch Signaling Activity.PMID 33171957Read ↗

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