Article
Longevity-Associated FOXO3 Genotype and its Impact on Coronary Artery Disease Mortality in Japanese, Whites, and Blacks: A Prospective Study of Three American Populations.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 May 2017
Willcox Bradley J, Morris Brian J, Tranah Gregory J, Chen Randi, Masaki Kamal H, He Qimei, Willcox D Craig, Allsopp Richard C, Moisyadi Stefan, Gerschenson Mariana, Davy Philip M C, Poon Leonard W, Rodriguez Beatriz, Newman Anne B, Harris Tamara B, Cummings Steven R, Liu Yongmei, Parimi Neeta, Evans Daniel S, Donlon Timothy A
Abstract excerpt
BACKGROUND: We recently reported that protection against coronary artery disease (CAD) mortality is the major contributor to longer life associated with FOXO3 genotype. The present study examined this relation in more detail. METHODS: We performed a 15-year observational study of 3,584 older American men of Japanese ancestry from the Kuakini Honolulu Heart Program cohort and 1,595 White and 1,067 Black elderly...
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