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Article

Forkhead box O3 longevity genotype may attenuate the impact of hypertension on risk of intracerebral haemorrhage.

Journal of hypertension - 1 Nov 2022

Nakagawa Kazuma, Chen Randi, Greenberg Steven M, Ross G Webster, Willcox Bradley J, Donlon Timothy A, Allsopp Richard C, Willcox D Craig, Morris Brian J, Masaki Kamal H

Abstract excerpt

OBJECTIVE: Since the G allele of forkhead box O3 ( FOXO3 ) single nucleotide polymorphism (SNP) rs2802292 is associated with resilience and longevity, ostensibly by mitigating the adverse effects of chronic cardiometabolic stress on mortality, our aim was to determine the association between the FOXO3 SNP rs2802292 genotype and risk of hypertension-mediated intracerebral haemorrhage (ICH). METHODS: From a...

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Source

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Identifiers

PMID: 35943066
DOI: 10.1097/HJH.0000000000003249
PMCID: PMC9553272

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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