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Article

Influence of common variants of TLR4 and TLR9 on clinical outcomes of Plasmodium falciparum malaria in Odisha, India.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2015

Kar Avishek, Panigrahi Subhendu, Tripathy Sagnika, Mohapatra Manoj K, Tayung Kumananda, Dhangadamajhi Gunanidhi

Abstract excerpt

BACKGROUND: In malaria, the toll-like receptors (TLRs) have recently emerged as major player of innate immunity. However, implication of TLR variants on clinical manifestations of malaria is conflicting. The present study aims to provide relevant information of growing interest in understanding the role of TLR4D299G, TLR9T-1237C and TLR9T-1486C polymorphisms on clinical outcomes of malaria. METHODS: We genotyped...

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Source

Identifiers

PMID: 26462624
DOI: 10.1016/j.meegid.2015.10.008

Genes

TLR9
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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