Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common virulence gene expression in adult first-time infected malaria patients and severe cases

28 Apr 2021

Abstract excerpt

Sequestration of Plasmodium falciparum ( P. falciparum )-infected erythrocytes to host endothelium through the parasite-derived P. falciparum erythrocyte membrane protein 1 ( Pf EMP1) adhesion proteins is central to the development of malaria pathogenesis. Pf EMP1 proteins have diversified and expanded to encompass many sequence variants, conferring each parasite a similar array of human endothelial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Drug Discovery Methods
Share to Malaria Research and Control
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33908865
DOI: 10.7554/elife.69040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common virulence gene expression in adult first-time infected malaria patients and severe casesPMID 33908865Read ↗

Gene expression profiling of malaria parasites reveals common virulence gene expression in adult first-time infected patients and severe casesSemantic proximity Read ↗

Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domainsSemantic proximity Read ↗

The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1Semantic proximity Read ↗

Expression of specific <i>var</i> gene subtypes is differentially associated with severe malaria syndromesSemantic proximity Read ↗

DC8 and DC13 var Genes Associated with Severe Malaria Bind Avidly to Diverse Endothelial CellsSemantic proximity Read ↗

<i>Plasmodium falciparum</i> erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in childrenSemantic proximity Read ↗

Severe adult malaria is associated with specific PfEMP1 adhesion types and high parasite biomassSemantic proximity Read ↗

Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral MalariaSemantic proximity Read ↗

Reconstructing ICAM-1-binding var genes of Plasmodium falciparumSemantic proximity Read ↗

Structural and genomic analysis of single nucleotide polymorphisms in human host factor endothelial protein C receptor (EPCR) reveals complex interplay with malaria parasites.Semantic proximity Read ↗

Plasmodium falciparum expresses fewer var genes at lower levels during asymptomatic dry season infections than clinical malaria casesSemantic proximity Read ↗

Homology blocks of Plasmodium falciparum var genes and clinically distinct forms of severe malaria in a local population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.