Article
Osteomalacia induced by long-term low-dose adefovir dipivoxil: Clinical characteristics and genetic predictors.
Bone - 1 Dec 2016
Wei Zhe, He Jin-Wei, Fu Wen-Zhen, Zhang Zhen-Lin
Abstract excerpt
CONTEXT: Adefovir dipivoxil (ADV) was an important cause of adult-onset hypophosphatemic osteomalacia. However, its clinical characteristics and mechanisms have not been well defined. OBJECTIVE: The objective of the study was to summarize the clinical characteristics of ADV-induced osteomalacia and to explore the association between ADV-associated tubulopathy and polymorphisms in genes encoding drug transporters....
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