Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms associated with renal adverse effects of antiretroviral therapy in a Southern Brazilian HIV cohort.

Pharmacogenetics and genomics - 1 Nov 2015

da Rocha Ivete M, Gasparotto Aline S, Lazzaretti Rosmeri K, Notti Regina K, Sprinz Eduardo, Mattevi Vanessa S

Abstract excerpt

OBJECTIVE: This study evaluated the impact of seven single nucleotide polymorphisms in five candidate genes (ABCB1, ABCC2, ABCC4, SLC22A6, and SLC22A11) in relation to nephrotoxicity associated with highly active antiretroviral therapy (HAART) in HIV-infected individuals. METHODS: The following single nucleotide polymorphisms were genotyped by real-time PCR: ABCB1 rs1045642, ABCC2 rs717620 and rs2273697, ABCC4...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Antiretroviral Therapy, Highly Active
Share to ATP Binding Cassette Transporter, Subfamily B
Share to Glomerular Filtration Rate
Share to Multidrug Resistance-Associated Protein 2
Share to Multidrug Resistance-Associated Proteins
Share to Organic Anion Transporters, Sodium-Independent
Share to Renal Insufficiency, Chronic

Source

Identifiers

PMID: 26287941
DOI: 10.1097/FPC.0000000000000169

Genes

ABCC2
ABCB1
ABCC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms associated with renal adverse effects of antiretroviral therapy in a Southern Brazilian HIV cohort.PMID 26287941Read ↗

A Single-Nucleotide Polymorphism in ABCC4 Is Associated with Tenofovir-Related Beta2-Microglobulinuria in Thai Patients with HIV-1 Infection.Semantic proximity Read ↗

Clinical and genetic factors associated with kidney tubular dysfunction in a real-life single centre cohort of HIV-positive patients.Semantic proximity Read ↗

ABCB1 and ABCC1 variants associated with virological failure of first-line protease inhibitors antiretroviral regimens in Northeast Brazil patients.Semantic proximity Read ↗

Single nucleotide polymorphisms in ABCC2 associate with tenofovir-induced kidney tubular dysfunction in Japanese patients with HIV-1 infection: a pharmacogenetic study.Semantic proximity Read ↗

Pharmacogenetic considerations for HIV treatment in different ethnicities: an update.Semantic proximity Read ↗

Single-nucleotide polymorphisms in the UDP-glucuronosyltransferase 1A-3' untranslated region are associated with atazanavir-induced nephrolithiasis in patients with HIV-1 infection: a pharmacogenetic study.Semantic proximity Read ↗

HIV-associated nephropathy: Protocol and rationale for an exploratory genotype-phenotype study in a sub-Saharan African population.Semantic proximity Read ↗

Apolipoprotein L1 gene variants and kidney disease in patients with HIV: a systematic review and meta-analysis.Semantic proximity Read ↗

ABCB1 variation and treatment response in AIDS patients: initial results of the Henan cohort.Semantic proximity Read ↗

Genetic Variants of APOL1 Are Major Determinants of Kidney Failure in People of African Ancestry With HIVSemantic proximity Read ↗

Prevalence of ABCC3-1767G/A polymorphism among patients with antiretroviral-associated hepatotoxicity.Semantic proximity Read ↗

Advances in the pathogenesis of HIV-associated kidney diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.