Single-nucleotide polymorphisms in the UDP-glucuronosyltransferase 1A-3' untranslated region are associated with atazanavir-induced nephrolithiasis in patients with HIV-1 infection: a pharmacogenetic study.

doi:10.1093/jac/dku304

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Article

Single-nucleotide polymorphisms in the UDP-glucuronosyltransferase 1A-3' untranslated region are associated with atazanavir-induced nephrolithiasis in patients with HIV-1 infection: a pharmacogenetic study.

The Journal of antimicrobial chemotherapy - 1 Dec 2014

Nishijima Takeshi, Tsuchiya Kiyoto, Tanaka Noriko, Joya Akane, Hamada Yohei, Mizushima Daisuke, Aoki Takahiro, Watanabe Koji, Kinai Ei, Honda Haruhito, Yazaki Hirohisa, Tanuma Junko, Tsukada Kunihisa, Teruya Katsuji, Kikuchi Yoshimi, Oka Shinichi, Gatanaga Hiroyuki

Abstract excerpt

OBJECTIVES: Ritonavir-boosted atazanavir (atazanavir/ritonavir) is a widely used antiretroviral drug, though it can potentially cause nephrolithiasis. The aim of this study was to determine the relationship between polymorphisms in genes encoding proteins involved in metabolism and transportation of atazanavir, and atazanavir/ritonavir-induced nephrolithiasis in HIV-1-infected patients treated with...

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PMID: 25151207
DOI: 10.1093/jac/dku304

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ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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