Article
Meta-analysis of loci associated with age at natural menopause in African-American women.
Human molecular genetics - 15 Jun 2014
Chen Christina T L, Liu Ching-Ti, Chen Gary K, Andrews Jeanette S, Arnold Alice M, Dreyfus Jill, Franceschini Nora, Garcia Melissa E, Kerr Kathleen F, Li Guo, Lohman Kurt K, Musani Solomon K, Nalls Michael A, Raffel Leslie J, Smith Jennifer, Ambrosone Christine B, Bandera Elisa V, Bernstein Leslie, Britton Angela, Brzyski Robert G, Cappola Anne, Carlson Christopher S, Couper David, Deming Sandra L, Goodarzi Mark O, Heiss Gerardo, John Esther M, Lu Xiaoning, Le Marchand Loic, Marciante Kristin, Mcknight Barbara, Millikan Robert, Nock Nora L, Olshan Andrew F, Press Michael F, Vaiyda Dhananjay, Woods Nancy F, Taylor Herman A, Zhao Wei, Zheng Wei, Evans Michele K, Harris Tamara B, Henderson Brian E, Kardia Sharon L R, Kooperberg Charles, Liu Yongmei, Mosley Thomas H, Psaty Bruce, Wellons Melissa, Windham Beverly G, Zonderman Alan B, Cupples L Adrienne, Demerath Ellen W, Haiman Christopher, Murabito Joanne M, Rajkovic Aleksandar
Abstract excerpt
Age at menopause marks the end of a woman's reproductive life and its timing associates with risks for cancer, cardiovascular and bone disorders. GWAS and candidate gene studies conducted in women of European ancestry have identified 27 loci associated with age at menopause. The relevance of these loci to women of African ancestry has not been previously studied. We therefore sought to uncover additional...
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