Article
Evaluating GWAS-identified SNPs for age at natural menopause among chinese women.
PloS one - 1 Jan 2013
Shen Chong, Delahanty Ryan J, Gao Yu-Tang, Lu Wei, Xiang Yong-Bing, Zheng Ying, Cai Qiuyin, Zheng Wei, Shu Xiao-Ou, Long Jirong
Abstract excerpt
BACKGROUND: Age at natural menopause (ANM) is a complex trait with high heritability and is associated with several major hormonal-related diseases. Recently, several genome-wide association studies (GWAS), conducted exclusively among women of European ancestry, have discovered dozens of genetic loci influencing ANM. No study has been conducted to evaluate whether these findings can be generalized to Chinese...
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