Article
Evidence of positive selection and concerted evolution in the rapidly evolving PRDM9 zinc finger domain in goats and sheep.
Animal genetics - 1 Dec 2016
Ahlawat S, Sharma P, Sharma R, Arora R, Verma N K, Brahma B, Mishra P, De S
Abstract excerpt
Meiotic recombination contributes to augmentation of genetic diversity, exclusion of deleterious alleles and proper segregation of chromatids. PRDM9 has been identified as the gene responsible for specifying the location of recombination hotspots during meiosis and is also the only known vertebrate gene associated with reproductive isolation between species. PRDM9 encodes a protein with a highly variable zinc...
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