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Article

Evolution of the recombination regulator PRDM9 in minke whales.

BMC genomics - 16 Mar 2022

Damm Elena, Ullrich Kristian K, Amos William B, Odenthal-Hesse Linda

Abstract excerpt

BACKGROUND: PRDM9 is a key regulator of meiotic recombination in most metazoans, responsible for reshuffling parental genomes. During meiosis, the PRDM9 protein recognizes and binds specific target motifs via its array of C2H2 zinc-fingers encoded by a rapidly evolving minisatellite. The gene coding for PRDM9 is the only speciation gene identified in vertebrates to date and shows high variation, particularly in...

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Identifiers

PMID: 35296233
DOI: 10.1186/s12864-022-08305-1
PMCID: PMC8925151

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