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Article

The chromodomain protein MRG-1 facilitates SC-independent homologous pairing during meiosis in Caenorhabditis elegans.

Developmental cell - 13 Dec 2011

Dombecki Carolyn R, Chiang Ason C Y, Kang Hyun-Joo, Bilgir Ceyda, Stefanski Nicholas A, Neva Bryan J, Klerkx Elke P F, Nabeshima Kentaro

Abstract excerpt

Homologous chromosome pairing is a prerequisite to establish physical linkage between homologs, which is critical for faithful chromosome segregation during meiosis I. The establishment of pairing is genetically separable from subsequent synapsis, defined as stabilization of pairing by the synaptonemal complex (SC). The underlying mechanism of presynaptic pairing is poorly understood. In the nematode...

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PMID: 22172672
DOI: 10.1016/j.devcel.2011.09.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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