Article
HTP-1 coordinates synaptonemal complex assembly with homolog alignment during meiosis in C. elegans.
Genes & development - 15 Nov 2005
Couteau Florence, Zetka Monique
Abstract excerpt
During meiosis, the mechanisms responsible for homolog alignment, synapsis, and recombination are precisely coordinated to culminate in the formation of crossovers capable of directing accurate chromosome segregation. An outstanding question is how the cell ensures that the structural hallmark of meiosis, the synaptonemal complex (SC), forms only between aligned pairs of homologous chromosomes. In the present...
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