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Article

Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C. elegans.

Genes & development - 15 Sept 2002

MacQueen Amy J, Colaiácovo Mónica P, McDonald Kent, Villeneuve Anne M

Abstract excerpt

Analysis of Caenorhabditis elegans syp-1 mutants reveals that both synapsis-dependent and -independent mechanisms contribute to stable, productive alignment of homologous chromosomes during meiotic prophase. Early prophase nuclei undergo normal reorganization in syp-1 mutants, and chromosomes initially pair. However, the polarized nuclear organization characteristic of early prophase persists for a prolonged...

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Identifiers

PMID: 12231631
DOI: 10.1101/gad.1011602
PMCID: PMC187442

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SYP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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