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Article

DNA methylation at birth within the promoter of ANRIL predicts markers of cardiovascular risk at 9 years.

Clinical epigenetics - 1 Jan 2016

Murray Robert, Bryant Jennifer, Titcombe Phil, Barton Sheila J, Inskip Hazel, Harvey Nicholas C, Cooper Cyrus, Lillycrop Karen, Hanson Mark, Godfrey Keith M

Abstract excerpt

AIMS: Antisense non-coding RNA in the INK4 locus (ANRIL) fixed genetic variants have consistently been linked with coronary heart disease (CHD) risk. We investigated relationships between perinatal ANRIL promoter DNA methylation and CHD risk markers in children aged 9 years. Genetic variants in the non-coding RNA ANRIL identify it as an important CHD risk locus. Increasing evidence suggests that the early life...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27594927
DOI: 10.1186/s13148-016-0259-5
PMCID: PMC5010744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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